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After joining the Royal Free Rheumatology Unit in 1990 as a medical registrar Professor Denton trained in rheumatology and scleroderma in the UK and North America, and in 2000 having completed his training, and gained a PhD in scleroderma-based laboratory research, returned to the Royal Free to work with Professor Black and Dr Geraldine Brough in the connective tissue diseases clinic, and supervise the registrars and other members of the team looking after inpatients on the rheumatology ward. Dr Denton became Professor Denton in 2006.

As well as treating patients with scleroderma and related disorders he has a major interest in clinical and laboratory research and supervise his own group of scientists in the laboratory, working closely with Dr David Abraham. Professor Denton's clinical research is focused on developing and improving methods for assessing scleroderma and using advances in understanding the events leading to scleroderma to develop new treatments. A major focus is the development of laboratory models for scleroderma so that new therapies can be evaluated thoroughly before they are tried in patients.
Professor Chris Denton
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